The Wisconsin company opened in 1999, when about 27% of postmenopausal women used hormone therapy, and its lab-monitored model now meets a market changed by the FDA’s 2025 label revision.
Renew Youth opened in 1999, when about 27% of postmenopausal American women were using hormone therapy. In 2002, findings from the Women’s Health Initiative suggested that combined estrogen and progesterone therapy could raise the risk of cardiovascular problems, breast cancer, endometrial cancer, and possibly dementia, and the FDA placed boxed warnings on estrogen treatments for menopause. By March 2020, use had fallen to around 5%, according to Harvard Health Publishing.
The Wisconsin company kept working in hormone therapy and longevity medicine through those years, by its own account, with a model built around what happens after a prescription is written.
In November 2025, the FDA began removing the boxed warnings on menopausal hormone therapy that referred to cardiovascular disease, breast cancer, and probable dementia. For the roughly 1.3 million American women who enter menopause each year, according to StatPearls, the change puts hormone therapy back on the list of options to discuss with a doctor. It also makes monitoring, who does it and how often, the thing that separates one provider from the next.
What the Warnings Changed
“They frightened many women who were very appropriate for hormone therapy and told them it was dangerous, when in reality the risks were quite low,” Dr. Kathryn Corelli, an internist and menopause specialist at Harvard-affiliated Brigham and Women’s Hospital, said in Harvard Health’s coverage of the decision. She advises an individualized conversation with a doctor that weighs age, years since menopause began, symptoms, and personal and family history of disease.
How Renew Woman Works
Renew Youth’s program for women, Renew Woman, begins with a free consultation. The company arranges lab work near the client through national accounts with two of the largest lab companies in the country, with home phlebotomist visits and at-home kits as alternatives. After reviewing the results and having an appointment with the client, a Renew Youth physician writes the treatment plan, which can include estrogen, progesterone, and testosterone therapy, DHEA and pregnenolone, and thyroid therapy. Treatments that promote longevity, weight loss, adrenal balance, and sexual health are also available. The company describes its hormones as bioidentical. Treatment is self-administered at home, and medication is shipped to the client.
“Every plan starts with lab work, so the treatment is tailored to what that woman needs,” said Nicole Michels, one of Renew Youth’s owners. “From there we fine-tune the dosing using her follow-up labs and how she tells us she feels.”
Six Months Between Tests
Renew Youth works with more than fifty physicians across the United States. Repeat labs come every six months, and dosing changes follow those results and the client’s own account of her symptoms.
“Hormone therapy has to be administered and monitored appropriately,” Michels said. “That is why our clients have their labs repeated every six months, and why their Renew Youth physician adjusts the plan from those results.”
Most hormone therapies are not covered by insurance. Renew Youth’s hormone therapy programs start from $200 a month, and the company accepts all major HSA and FSA debit cards.
A Decision Still Made With a Physician
Whether any woman should take hormones remains a decision for her and her physician, a point Corelli and the Menopause Society both make. For those who have that conversation, Renew Youth offers something specific to ask about: repeat labs every six months and a physician who changes the dosing when the results change. The company has been in the field since 1999 and stayed in it through the two decades when most women came off hormone therapy.
