The humble toothbrush has barely changed in over a century, yet nearly 40 percent of adults still develop gum disease despite diligent brushing. ZERObrush, an emerging oral care technology company, is seeking to change that, and investors are taking notice.
Co-founded by cosmetic dentist Dr. Nidhi Pai and product innovator Akash Pai, ZERObrush is developing the world’s first full-mouth oral cleaning device, a fully automated system designed to clean every tooth surface simultaneously. The device combines advanced 3D scanning, custom-fit mouthpieces, and sonic-powered bristles, delivering a professional-level clean at home in a fraction of the time it takes with manual brushing.
“This device represents a major breakthrough in oral hygiene,” said Dr. Nidhi Pai, practicing cosmetic dentist and co-founder of ZERObrush. “Despite regular brushing, many people continue to develop gum disease and other oral health issues because traditional brushes simply cannot clean all tooth surfaces effectively. ZERObrush solves this longstanding clinical problem by delivering a full-mouth clean customized to each individual’s unique dental anatomy.”
Unlike recent “full-mouth” devices that attempt a one-size-fits-all approach, ZERObrush emphasizes personalization. Each mouthpiece is created from a precise 3D model of the user’s teeth, placing bristles exactly where they are needed to remove plaque thoroughly while protecting sensitive gums. Early clinical trials have shown that the device removes significantly more plaque than manual brushing, reduces gum irritation, and simplifies daily oral care.
Early Clinical Findings
Clinical results highlight just how different the experience can be. In just 30 seconds, ZERObrush removed nearly twice as much plaque as a manual toothbrush did in a full minute. After four weeks of use, participants had significantly less plaque buildup, while those brushing manually actually saw plaque increase. The device was also up to five times more effective at reaching the most difficult spots, like the backs of teeth and along the gumline. Gum health improved as well: ZERObrush reduced gum inflammation and bleeding over the same period, while manual brushing made these issues worse.
Backing from Major Investors Highlights Market Confidence
ZERObrush has raised $10.8 million in financing to date, securing support from prominent investors including Large CPG Strategic, Social Capital, several angel investors, and a senior executive from Meta. This financial backing underscores the market’s confidence in ZERObrush’s potential to define a new category in oral care.
“Oral care has remained largely unchanged for over a century despite clear evidence that traditional brushing leaves many tooth surfaces inadequately cleaned,” said Dr. Pai. “Zerobrush is not just an incremental improvement — it’s a completely new category of oral hygiene that brings professional-level cleaning to everyday routines.”
The ZERObrush system relies on advanced 3D printing, specialized materials, and software adapted from other industries to deliver a truly customized and effective cleaning experience. By targeting all 192 tooth surfaces simultaneously, the device provides a precision clean that even skilled manual brushing can’t match.
Co-founder Akash Pai, who led the product’s design and engineering, said the team’s approach was guided by a commitment to personalization and clinical rigor.
“We resisted the industry’s push for one-size-fits-all products,” he said. “Instead, we leveraged cutting-edge technology to deliver superior plaque removal while protecting sensitive gum tissue — making daily oral care faster, easier, and more effective.”
ZERObrush is preparing for a commercial launch in 2026. People can sign up now to be considered for upcoming product trials, which begin with a brief survey to determine eligibility.
Dentists and early adopters interested in learning more about ZERObrush can visit ZERObrush. With robust funding, a visionary team, and pioneering technology, ZERObrush is poised to redefine what clean teeth and healthy gums look like in the 21st century.
