From Chronic Pain to Nervous-System Wellness: How Jaime Alefosio Built Hey Mary Jane

By Spencer Hulse Spencer Hulse has been verified by Muck Rack's editorial team
Published on February 11, 2026

For high-achieving professionals, burnout has become almost a badge of honor. Endless to-do lists, sleepless nights, and a constant state of “go mode” are often treated as normal—but what if the key to thriving wasn’t pushing harder, but regulating the very system that drives stress?

Jaime Alefosio knows this all too well. After decades of struggling with undiagnosed Lyme disease and chronic pain, she found herself trapped in a cycle of fatigue, anxiety, and overwhelm. Years of pushing through symptoms had left her depleted. Pharmaceuticals helped, but they didn’t address the root cause: a nervous system stuck in survival mode.

“Women are running entire worlds—families, careers, the emotional labor no one sees—and we’re doing it on nervous systems that are completely burned out,” Jaime says. “Hey Mary Jane came from my own crash-and-rebuild journey. Micro-dosed wellness gives you permission to stop surviving and start regulating again.”

That realization became the foundation for Hey Mary Jane, a functional wellness brand built around micro-dosed cannabinoids blended with adaptogens, nootropics, and amino acids. The goal isn’t intoxication—it’s balance.

Jaime describes the brand as “wellness first.” Cannabinoids are just one part of a broader formula designed to support sleep, focus, hormone rhythm, inflammation, and emotional bandwidth. Each product—Drift for sleep, Groove for creative flow, Soothe for pain relief, and Fit for hormonal support—uses intentional micro-dosing (under 3mg of THC) to create subtle but meaningful shifts without sedation or cognitive fog.

At the heart of the brand is a rejection of extremes. Women, Jaime believes, are tired of being either overstimulated by caffeine and stress or knocked out by heavy sleep aids and pharmaceuticals. Micro-dosing offers a middle ground—present, clear, and regulated.

“There’s so much shame around needing support,” she explains. “Women are expected to be endlessly strong, endlessly available, endlessly ‘fine.’ I created Hey Mary Jane because sometimes you’re not fine—and that doesn’t make you weak. Micro-dosing is a way to gently regulate without checking out.”

Rather than overriding the body’s signals, Jaime emphasizes working with them. Chronic stress, trauma, and long-term pressure, she says, quietly erode capacity over time. Nervous-system support isn’t indulgent—it’s foundational.

“We’ve been conditioned to push through everything—pain, fatigue, dysregulation. That mindset nearly broke me. Micro-dosing doesn’t fix your life, but it gives your body the space to recalibrate so you can actually feel your way through it.”

Jaime is a board-certified Exponential Health Coach and is currently pursuing her Doctor of Natural Medicine degree, blending formal study with lived experience. Her approach combines plant medicine, neuroscience, and strategic brand-building—positioning cannabinoids not as recreational escape, but as tools for intentional regulation.

In a world that glorifies burnout, Hey Mary Jane reframes wellness as regulation—not escape. And for high-functioning women running on empty, that small-but-real shift may be exactly what brings them back online.

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By Spencer Hulse Spencer Hulse has been verified by Muck Rack's editorial team

Spencer Hulse is the Editorial Director at Grit Daily. He is responsible for overseeing other editors and writers, day-to-day operations, and covering breaking news.

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